Smad1/9 antibody (AA 400-465)
Quick Overview for Smad1/9 antibody (AA 400-465) (ABIN8124750)
Target
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 400-465
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Purpose
- Smad1/9 mouse mAb
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Specificity
- This antibody detects endogenous levels of Smad1/9 protein.
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Purification
- The antibody was purified by protein G affinity chromatography.
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Immunogen
- A synthetic peptide corresponding to the amino acid region 400 - 465 of the human Smad1/9 protein.
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Isotype
- IgG
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anti-Smad1/9 (C-Term) antibody
Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
anti-Smad1/9 (pSer465), (pSer467) antibodyReactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid freeze / thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at-20°C. Avoid freeze / thaw cycles.
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- Smad1/9
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Background
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Synonyms: Mothers against decapentaplegic homolog 1, MAD homolog 1, Mothers against DPP homolog 1, JV4-1, Mad-related protein 1, SMAD family member 1 (SMAD 1, Smad1, hSMAD1) , Transforming growth factor-beta-signaling protein 1 (BSP-1) , SMAD1, BSP1, MADH1, MADR1, Mothers against decapentaplegic homolog 9, MAD homolog 9, Mothers against DPP homolog 9, Madh6, SMAD family member 9 (SMAD 9, Smad9) , SMAD9, MADH6, MADH9, SMAD8
Background: SMAD family member 1 (SMAD1) Homo sapiens The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs) , which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-med
Gene Name: SMAD1 SMAD9
Protein Name: Smad1/9
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Gene ID
- 4086
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UniProt
- Q15797
Target
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