Neural Wiskott-Aldrich syndrome protein (WASL) (Internal Region) antibody

Catalog No. ABIN6266010

The Rabbit Polyclonal anti-Neural Wiskott-Aldrich syndrome protein antibody is suitable to detect Neural Wiskott-Aldrich syndrome protein in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for Neural Wiskott-Aldrich syndrome protein (WASL) (Internal Region) antibody (ABIN6266010)

Target: Neural Wiskott-Aldrich syndrome protein (WASL)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details

Binding Specificity: Internal Region

Specificity: N-WASP Antibody detects endogenous levels of total N-WASP.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human N-WASP, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details

Target: Neural Wiskott-Aldrich syndrome protein (WASL)

Alternative Name: WASL

Background:

Description: Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression. Plays a role in dendrite spine morphogenesis (By similarity).

Gene: WASL

Molecular Weight: 54kDa

Gene ID: 8976

UniProt: O00401