YEATS2 antibody (Internal Region)

Catalog No. ABIN6266078

Product Details anti-YEATS2 Antibody

Target: YEATS2 (YEATS Domain Containing 2 (YEATS2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YEATS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: YEATS2 Antibody detects endogenous levels of total YEATS2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human YEATS2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for YEATS2

Target: YEATS2 (YEATS Domain Containing 2 (YEATS2))

Alternative Name: YEATS2 (YEATS2 Products)

Background:

Description: Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) (PubMed:27103431). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:27103431).

Gene: YEATS2

Molecular Weight: 150kDa

Gene ID: 55689

UniProt: Q9ULM3