ZKSCAN3 antibody (Internal Region)

Catalog No. ABIN6266108

This Rabbit Polyclonal antibody specifically detects ZKSCAN3 in ELISA, WB, IF and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for ZKSCAN3 antibody (Internal Region) (ABIN6266108)

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZKSCAN3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-ZKSCAN3 Antibody

Binding Specificity: Internal Region

Specificity: ZKSCAN3 Antibody detects endogenous levels of total ZKSCAN3.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZKSCAN3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ZKSCAN3

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Alternative Name: ZKSCAN3

Background:

Description: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.

Gene: ZKSCAN3

Molecular Weight: 61 kDa

Gene ID: 80317

UniProt: Q9BRR0