DCLK2 antibody (N-Term)

Catalog No. ABIN6287500

Product Details anti-DCLK2 Antibody

Target: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Binding Specificity: AA 1-80, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCLK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purpose: DCAMKL2 is a protein encoded by the DCLK2 gene which is approximately 83,6 kDa. DCAMKL2 is localised to the cytoplasm and is involved in transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. This protein falls under the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization. It also contains a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase. DCAMKL2 is expressed in the brain, heart and eye. The absence of this protein results in a severe epileptic phenotype and lethality. STJ92663 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of DCAMKL2 protein.

Specificity: DCAMKL2 Polyclonal Antibody detects endogenous levels of DCAMKL2 protein.

Characteristics: Rabbit polyclonal to DCAMKL2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human DCAMKL2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:10000

Comment:

Expressed in the brain, heart and eyes.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for DCLK2

Target: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Alternative Name: DCAMKL2 (DCLK2 Products)

Synonyms: CL2 antibody, CLICK-II antibody, CLICK2 antibody, CLIK2 antibody, DCAMKL2 antibody, DCDC3 antibody, DCDC3B antibody, DCK2 antibody, 6330415M09Rik antibody, AU044875 antibody, Click-II antibody, Dcamkl2 antibody, DCLK2 antibody, cb572 antibody, dclk antibody, sb:cb572 antibody, si:dkey-180n16.1 antibody, Dck2 antibody, RGD1308384 antibody, doublecortin like kinase 2 antibody, doublecortin-like kinase 2 antibody, doublecortin-like kinase 2a antibody, DCLK2 antibody, Dclk2 antibody, dclk2a antibody

Molecular Weight: 83 kDa

Gene ID: 166614

UniProt: Q8N568