LNPEP antibody

Catalog No. ABIN6291334

This Rabbit Polyclonal antibody specifically detects LNPEP in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for LNPEP antibody (ABIN6291334)

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNPEP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LNPEP Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human LNPEP

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Highly expressed in placenta, heart, kidney and small intestine, Detected at lower levels in neuronal cells in the brain, in skeletal muscle, spleen, liver, testes and colon

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for LNPEP

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Alternative Name: LNPEP

Background: This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 117.349 kDa

Gene ID: 4012

UniProt: Q9UIQ6

Pathways: Regulation of long-term Neuronal Synaptic Plasticity