LNPEP antibody (AA 1-50)

Catalog No. ABIN7450530

The Rabbit Polyclonal anti-LNPEP antibody (ABIN7450530) specifically detects LNPEP in WB and IP. The antibody is reactive with Human samples.

Quick Overview for LNPEP antibody (AA 1-50) (ABIN7450530)

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNPEP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-LNPEP Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-Oxytocinase Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for LNPEP

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Alternative Name: Oxytocinase

Background: Background: Oxytocinase is a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] [taken from NCBI Entrez Gene (Gene ID: 4012)]. [taken from the Universal Protein Resource (UniProt) Q9UIQ6].

Gene ID: 4012

NCBI Accession: NP_005566

UniProt: Q9UIQ6

Pathways: Regulation of long-term Neuronal Synaptic Plasticity