LNPEP antibody (AA 1-110)
Quick Overview for LNPEP antibody (AA 1-110) (ABIN6143284)
Target
See all LNPEP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-110
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Sequence
- MEPFTNDRLQ LPRNMIENSM FEEEPDVVDL AKEPCLHPLE PDEVEYEPRG SRLLVRGLGE HEMEEDEEDY ESSAKLLGMS FMNRSSGLRN SATGYRQSPD GACSVPSART
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human LNPEP (NP_005566.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))
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Alternative Name
- LNPEP
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Background
- This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.,LNPEP,CAP,IRAP,P-LAP,PLAP,Cell Biology & Developmental Biology,Ubiquitin,LNPEP
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Molecular Weight
- 115 kDa/117 kDa
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Gene ID
- 4012
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UniProt
- Q9UIQ6
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Pathways
- Regulation of long-term Neuronal Synaptic Plasticity
Target
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