BSCL2 antibody (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin))

Details for Product anti-BSCL2 Antibody No. ABIN6293870
Antigen
Reactivity
Mouse (Murine), Rat (Rattus)
33
2
2
2
2
2
1
1
1
Host
Rabbit
26
6
1
Clonality
Polyclonal
Conjugate
This BSCL2 antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
33
22
19
2
1
1
Options
Immunogen A synthetic peptide of human BSCL2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name BSCL2 (BSCL2 Antibody Abstract)
Background This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
Molecular Weight 44.392 kDa
Gene ID 26580
UniProt Q96G97
Application Notes WB 1:500 - 1:2000
Comment

Expressed in motor neurons in the spinal cord and cortical neurons in the frontal lobe (at protein level), Highly expressed in brain, testis and adipose tissue

Restrictions For Research Use only
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2) antibody (ABIN6293870) Western blot analysis of extracts of various cell lines, using BSCL2 antibody (ABIN62...