CFTR antibody (AA 258-385)
Quick Overview for CFTR antibody (AA 258-385) (ABIN6294432)
Target
See all CFTR AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 258-385
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Purpose
- Mouse anti-Human CFTR Antibody / Cystic Fibrosis Transmembrane Regulator [Sodium Azide Free]
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Specificity
- Cell surface, cytoplasmic
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Purification
- A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.
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Immunogen
- A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.
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Application Notes
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IF: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
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Alternative Name
- Cystic fibrosis transmembrane conductance regulator
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Background
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Target Description: Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
Gene Symbol: CFTR///ABCC7
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Gene ID
- 1080
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UniProt
- P13569
Target
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