Ubiquitin Hydrolase Isozyme L1 (C-Term) antibody

Catalog No. ABIN6294654

The Mouse Monoclonal anti-Ubiquitin Hydrolase Isozyme L1 antibody (ABIN6294654) specifically detects Ubiquitin Hydrolase Isozyme L1 in WB and IF. The antibody is reactive with Human, Rat, Cow, Mouse, Pig, Dog, Guinea Pig, Rabbit, Sheep and Zebrafish (Danio rerio) samples.

Quick Overview for Ubiquitin Hydrolase Isozyme L1 (C-Term) antibody (ABIN6294654)

Target: Ubiquitin Hydrolase Isozyme L1

Reactivity: Human, Rat, Cow, Mouse, Pig, Dog, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details

Binding Specificity: C-Term

Purpose: Mouse anti-Cow/Dog/Guinea pig/Human/Mouse/Pig/Rabbit/Rat/Sheep/Zebrafish UchL1 Antibody PGP9.5 [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: Native protein from brain was used as the immunogen for this UchL1 antibody.

Immunogen: Native protein from brain was used as the immunogen for this UchL1 antibody.

Application Details

Application Notes: WB: 0.5-1 μg/mL
IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details

Target: Ubiquitin Hydrolase Isozyme L1

Background:

Target Description: This antibody specifically reacts with a protein of 20-30 kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1), or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease.

Gene Symbol: UCHL1

Gene ID: 7345

UniProt: P09936