LMX1A antibody (Center)

Catalog No. ABIN6295155

The Rabbit Polyclonal anti-LMX1A antibody (ABIN6295155) specifically detects LMX1A. The antibody is reactive with Human and Mouse samples.

Quick Overview for LMX1A antibody (Center) (ABIN6295155)

Target: LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMX1A antibody is un-conjugated

Application: Please inquire

Product Details anti-LMX1A Antibody

Binding Specificity: AA 130-159, Center

Purpose: Rabbit Anti-Lmx1a (Center) Antibody

Immunogen: This Lmx1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human Lmx1a.

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for LMX1A

Target: LMX1A (LIM Homeobox Transcription Factor 1, alpha (LMX1A))

Alternative Name: Lmx1a

Background:

Target Description: Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin.

Gene Symbol: Lmx1a

Gene ID: 110648

UniProt: Q9JKU8

Pathways: Dopaminergic Neurogenesis