PD-1 antibody

Catalog No. ABIN6295971

The Rabbit Polyclonal anti-PD-1 antibody (ABIN6295971) specifically detects PD-1 in FACS, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for PD-1 antibody (ABIN6295971)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PD-1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PD-1 Antibody

Purpose: Rabbit anti-Human PDCD1 / PD-1 Antibody [Sodium Azide Free]

Specificity: Cell surface & cytoplasmic

Purification: A full-length human protein was used as the immunogen for the PD1 antibody.

Immunogen: A full-length human protein was used as the immunogen for the PD1 antibody.

Application Details

Application Notes: Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
Immunofluorescence: 1-2 μg/mL
FACS: 0.5-1 μg/10e6 cells in 0.1ml

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: Programmed cell death protein 1

Background:

Target Description: PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

Gene Symbol: PDCD1///PD1

Gene ID: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints