CD56 antibody

Catalog No. ABIN6296032

This Mouse Monoclonal antibody specifically detects CD56 in FACS, WB, IHC and IF. It exhibits reactivity toward Human, Rat and Zebrafish (Danio rerio).

Quick Overview for CD56 antibody (ABIN6296032)

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivity: Human, Rat, Zebrafish (Danio rerio)

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD56 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CD56 Antibody

Purpose: Mouse anti-Human/Rat/Zebrafish NCAM Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: A membrane preparation of a small cell lung carcinoma was used as the immunogen for this NCAM / CD56 antibody.

Immunogen: A membrane preparation of a small cell lung carcinoma was used as the immunogen for this NCAM / CD56 antibody.

Application Details

Application Notes: Western blot: 0.5-1 μg/mL
FACS:0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Alternative Name: Neural cell adhesion molecule 1

Background:

Target Description: This antibody reacts with an extracellular domain (close to transmembrane) of NCAM (Neural cell adhesion molecule), also called CD56. Three isoforms of NCAM / CD56 are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. NCAM antibody recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). NCAM antibody plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Gene Symbol: NCAM1///NCAM

Gene ID: 4684

UniProt: P13591