Calnexin antibody

Catalog No. ABIN6296055

This anti-Calnexin antibody is a Mouse Monoclonal antibody detecting Calnexin in WB, IHC, IF and FACS. Suitable for Human.

Quick Overview for Calnexin antibody (ABIN6296055)

Target: Calnexin (CANX)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-Calnexin Antibody

Purpose: Mouse anti-Human Calnexin Antibody [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

Immunogen: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

Application Details

Application Notes: WB: 0.5-1 μg/mL
FACS: 0.5-1 μg/10^6 cells
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: Calnexin  

Background:

Target Description: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Gene Symbol: CANX

Gene ID: 821

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis