AMACR antibody

Catalog No. ABIN6296086

This Mouse Monoclonal antibody specifically detects AMACR in IHC and IF. It exhibits reactivity toward Human.

Quick Overview for AMACR antibody (ABIN6296086)

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AMACR antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-AMACR Antibody

Purpose: Mouse anti-Human AMACR / p504S Antibody (Prostate Cancer Marker) [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: A recombinant human protein was used as the immunogen for the AMACR antibody.

Immunogen: A recombinant human protein was used as the immunogen for the AMACR antibody.

Application Details

Application Notes: Immunohistology (FFPE): 1-2 μg/mL for 30 minutes at RT
IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In sterile PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for AMACR

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Alternative Name: Alpha-methylacyl-CoA racemase

Background:

Target Description: AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.

Gene Symbol: AMACR

Gene ID: 23600

UniProt: Q9UHK6

Pathways: Monocarboxylic Acid Catabolic Process