Myeloid Cell Marker antibody

Catalog No. ABIN6296504

The Mouse Monoclonal anti-Myeloid Cell Marker antibody is suitable to detect Myeloid Cell Marker in samples from Human. It has been validated for IHC.

Quick Overview for Myeloid Cell Marker antibody (ABIN6296504)

Target: Myeloid Cell Marker

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Product Details

Purpose: Mouse anti-Human Myeloid Cell Marker Antibody [IHC only]

Specificity: Cytoplasmic and nuclear

Purification: Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.

Immunogen: Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details

Target: Myeloid Cell Marker

Background:

Target Description: This antibody recognizes a 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid cell specific antigen. Clone BM-1 antibody reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. This type of marker is useful in the identification of different levels of cellular differentiation. BM-1 and BM-2 antibodies react with early precursor and mature forms of human myeloid cells. This mAb is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of the marker protein is not clear, although it has been proposed that it may play a role in cell differentiation.