Myeloid Cell Marker antibody
Quick Overview for Myeloid Cell Marker antibody (ABIN6296505)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Purpose
- Mouse anti-Human Myeloid Cell Marker Antibody [Sodium Azide Free]
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Specificity
- Cytoplasmic and nuclear
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Purification
- Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.
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Immunogen
- Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.
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anti-Myeloid Cell Marker antibody
Reactivity: Human FACS, IF, IHC (p) Host: Mouse Monoclonal BM-1 unconjugated
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Application Notes
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FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Myeloid Cell Marker
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Background
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Target Description: This antibody recognizes a 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid cell specific antigen. Clone BM-1 antibody reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. This type of marker is useful in the identification of different levels of cellular differentiation. BM-1 and BM-2 antibodies react with early precursor and mature forms of human myeloid cells. This mAb is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of the marker protein is not clear, although it has been proposed that it may play a role in cell differentiation.
Target
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