CD22 antibody

Catalog No. ABIN6296528

The Mouse Monoclonal anti-CD22 antibody has been validated for FACS, IF and Func. It is suitable to detect CD22 in samples from Human, Mouse and Rat.

Quick Overview for CD22 antibody (ABIN6296528)

Target: CD22 (CD22 Molecule (CD22))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD22 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Product Details anti-CD22 Antibody

Purpose: Mouse anti-Human/Mouse/Rat CD22 Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: Human Raji cells were used as the immunogen for the CD22 antibody.

Immunogen: Human Raji cells were used as the immunogen for the CD22 antibody.

Application Details

Application Notes: Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD22

Target: CD22 (CD22 Molecule (CD22))

Alternative Name: B-cell receptor CD22

Background:

Target Description: Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

Gene Symbol: CD22///SIGLEC2

Gene ID: 933

UniProt: P20273