HSPD1 antibody

Catalog No. ABIN6297187

This Mouse Monoclonal antibody specifically detects HSPD1 in WB, IF and FACS. It exhibits reactivity toward Human, Mouse, Rat, Chicken, Monkey, Hamster, Guinea Pig, Nematode, Saccharomyces cerevisiae, E. coli, Spinach, Trichinella spiralis, Salmonella typhimurium, Bacteria (Treponema), Borrelia, Streptococcus pyogenes and Yersinia enterocolitica.

Quick Overview for HSPD1 antibody (ABIN6297187)

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Reactivity: Human, Mouse, Rat, Chicken, Monkey, Hamster, Guinea Pig, Nematode, Saccharomyces cerevisiae, E. coli, Spinach, Trichinella spiralis, Salmonella typhimurium, Bacteria (Treponema), Borrelia, Streptococcus pyogenes, Yersinia enterocolitica

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSPD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-HSPD1 Antibody

Purpose: Mouse anti-Human/Mouse/Rat/Hamster/Guinea pig/Monkey/Chicken/E. coli/Borellia/Bacteria/Helminths/Yeast/Spinach HSP60 Antibody [Sodium Azide Free]

Specificity: Mitochondria in cytoplasm

Purification: Recombinant human HSP60 protein was used as the immunogen for this antibody.

Immunogen: Recombinant human HSP60 protein was used as the immunogen for this antibody.

Application Details

Application Notes: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for HSPD1

Target: HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

Alternative Name: 60 kDa heat shock protein, mitochondrial

Background:

Target Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp 's), more appropriately called as stress response proteins (srp 's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.

Gene Symbol: HSPD1///HSP60

Gene ID: 3329

UniProt: P10809

Pathways: Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity