Progesterone Receptor antibody

Catalog No. ABIN6297262

This Mouse Monoclonal antibody specifically detects Progesterone Receptor in WB, IHC and ISt. It exhibits reactivity toward Human.

Quick Overview for Progesterone Receptor antibody (ABIN6297262)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunostaining (ISt)

Product Details anti-Progesterone Receptor Antibody

Purpose: Mouse anti-Human Progesterone Receptor Antibody [Sodium Azide Free]

Specificity: Nuclear

Purification: Recombinant human Progesterone Receptor protein was used as the immunogen for this antibody.

Immunogen: Recombinant human Progesterone Receptor protein was used as the immunogen for this antibody.

Application Details

Application Notes: WB: 0.5-1 μg/mL
Immunohistochemistry: 0.5-1 μg/mL (Cat No. V2224 is recommended for IHC)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: Progesterone receptor

Background:

Target Description: This antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of progesterone receptor has been suggested to reflect a intact estrogen regulatory machinery and therefore predict better clinical response to endocrine therapy than ER alone.

Gene Symbol: PGR///NR3C3

Gene ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration