VEGFR2/CD309 antibody

Catalog No. ABIN6297586

This Mouse Monoclonal antibody specifically detects VEGFR2/CD309 in FACS, IF and Func. It exhibits reactivity toward Human.

Quick Overview for VEGFR2/CD309 antibody (ABIN6297586)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VEGFR2/CD309 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Product Details anti-VEGFR2/CD309 Antibody

Purpose: Mouse anti-Human VEGFR2 Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: Recombinant human VEGFR2 protein was used as the immunogen for this antibody.

Immunogen: Recombinant human VEGFR2 protein was used as the immunogen for this antibody.

Application Details

Application Notes: Functional testing: order BSA/azide-free format
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name: Vascular endothelial growth factor receptor 2

Background:

Target Description: VEGFR2 ( also called CD309, KDR3, and Flk-1) is a type I transmembrane glycoprotein and is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. As a receptor for VEGF proteins, it plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability.

Gene Symbol: KDR///FLK1///VEGFR2

Gene ID: 3791

UniProt: P35968

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling