TYR antibody

Catalog No. ABIN6297624

This anti-TYR antibody is a Mouse Monoclonal antibody detecting TYR in IHC. Suitable for Human.

Quick Overview for TYR antibody (ABIN6297624)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TYR antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-TYR Antibody

Purpose: Mouse anti-Human Tyrosinase Antibody [IHC only]

Specificity: Cytoplasmic

Purification: Recombinant Tyrosinase protein was used as the immunogen for this antibody.

Immunogen: Recombinant Tyrosinase protein was used as the immunogen for this antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: Tyrosinase

Background:

Target Description: Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.

Gene Symbol: TYR

Gene ID: 7299

UniProt: P14679