TYR antibody

Catalog No. ABIN6297625

This Mouse Monoclonal antibody specifically detects TYR in WB, IHC, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for TYR antibody (ABIN6297625)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TYR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-TYR Antibody

Purpose: Mouse anti-Human Tyrosinase Antibody [Sodium Azide Free]

Specificity: Cytoplasmic

Purification: Recombinant Tyrosinase protein was used as the immunogen for this antibody.

Immunogen: Recombinant Tyrosinase protein was used as the immunogen for this antibody.

Application Details

Application Notes: Western blot: 2-5 μg/mL
FACS:0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: Tyrosinase

Background:

Target Description: Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients.

Gene Symbol: TYR

Gene ID: 7299

UniProt: P14679