Prolactin Receptor antibody

Catalog No. ABIN6297634

This Mouse Monoclonal antibody specifically detects Prolactin Receptor in IHC, FACS and IF. It exhibits reactivity toward Human.

Quick Overview for Prolactin Receptor antibody (ABIN6297634)

Target: Prolactin Receptor (PRLR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-Prolactin Receptor Antibody

Purpose: Mouse anti-Human Prolactin Receptor Antibody Cocktail [Sodium Azide Free]

Specificity: Cell surface and cytoplasmic

Purification: Semi-purified human prolactin receptor (B6.2) and recombinant human protein (PRLR742) were used as the immunogens for this Prolactin Receptor antibody cocktail.

Immunogen: Semi-purified human prolactin receptor (B6.2) and recombinant human protein (PRLR742) were used as the immunogens for this Prolactin Receptor antibody cocktail.

Application Details

Application Notes: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: Prolactin receptor

Background:

Target Description: It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Gene Symbol: PRLR

Gene ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus