Cytokeratin 1 antibody

Catalog No. ABIN6297650

The Mouse Monoclonal anti-Cytokeratin 1 antibody has been validated for IHC. It is suitable to detect Cytokeratin 1 in samples from Human, Rat, Mouse, Cow, Rabbit, Chicken, Monkey and Dog.

Quick Overview for Cytokeratin 1 antibody (ABIN6297650)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Chicken, Monkey, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cytokeratin 1 Antibody

Purpose: Mouse anti-Human/Monkey/Cow/Dog/Rabbit/Mouse/Rat/Chicken Basic Cytokeratin Antibody [IHC only]

Specificity: Cytoplasmic

Purification: Solubilized cytokeratin extract from human stratum corneum was used as the immunogen.

Immunogen: Solubilized cytokeratin extract from human stratum corneum was used as the immunogen.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Alternative Name: Keratin, type II cytoskeletal 1

Background:

Target Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8). Many studies have shown the usefulness of keratin markers in cancer research and tumor diagnosis. The basic family clone AE3 is commonly used in combination with clone AE1 as a pan cytokeratin antibody acidic + basic cocktail (< a href=../pan-cytokeratin-antibody-cocktail-ae1-ae3-v2330>Cat No V2330).

Gene Symbol: KRT1///KRTA

Gene ID: 3848

UniProt: P04264