Intercellular Adhesion Molecule 3 (ICAM3) antibody

Details for Product No. ABIN6297675
Antigen
  • CD50
  • CDW50
  • ICAM-R
  • ICAM-3
  • ICAM3
  • intercellular adhesion molecule 3
  • ICAM3
  • Icam3
Reactivity
Human
329
5
5
4
2
Host
Mouse
245
82
1
Clonality
Monoclonal
Conjugate
Un-conjugated
19
17
15
7
6
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF), Immunohistochemistry (IHC)
204
154
123
83
79
73
63
53
14
11
10
8
8
6
6
4
4
4
2
2
1
1
Options
Purpose Mouse anti-Human ICAM-3 Antibody [Sodium Azide Free]
Immunogen Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.
Specificity Cell surface
Purification Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.
Antigen
Alternative Name Intercellular adhesion molecule 3 (ICAM3 Antibody Abstract)
Background

Target Description: Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb is excellent for staining of formalin/paraffin tissues.

Gene Symbol: ICAM3

Gene ID 3385
UniProt P32942
Application Notes Functional Activity: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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