ICAM-3/CD50 antibody

Catalog No. ABIN6297703

This Mouse Monoclonal antibody specifically detects ICAM-3/CD50 in IHC. It exhibits reactivity toward Human.

Quick Overview for ICAM-3/CD50 antibody (ABIN6297703)

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM-3/CD50 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-ICAM-3/CD50 Antibody

Purpose: Mouse anti-Human CD50 Antibody [IHC only]

Specificity: Cell surface

Purification: Stimulated human leukocytes were used as the immunogen for this CD50 antibody.

Immunogen: Stimulated human leukocytes were used as the immunogen for this CD50 antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for ICAM-3/CD50

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Alternative Name: Intercellular adhesion molecule 3

Background:

Target Description: This antibody recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM3 (Leucocyte Workshop VI). It is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This CD50 antibody is excellent for staining of formalin/paraffin tissues.

Gene Symbol: ICAM3

Gene ID: 3385

UniProt: P32942