Intercellular Adhesion Molecule 3 (ICAM3) antibody

Details for Product No. ABIN6297704
Antigen
  • CD50
  • CDW50
  • ICAM-R
  • ICAM-3
  • ICAM3
  • intercellular adhesion molecule 3
  • ICAM3
  • Icam3
Reactivity
Human
329
5
5
4
2
Host
Mouse
245
82
1
Clonality
Monoclonal
Conjugate
Un-conjugated
19
17
15
7
6
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
Blocking Peptide (BP), Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF), Immunohistochemistry (IHC)
204
154
123
83
79
73
63
53
14
11
10
8
8
6
6
4
4
4
2
1
1
1
Options
Purpose Mouse anti-Human CD50 Antibody [Sodium Azide Free]
Immunogen Stimulated human leukocytes were used as the immunogen for this CD50 antibody.
Specificity Cell surface
Purification Stimulated human leukocytes were used as the immunogen for this CD50 antibody.
Antigen
Alternative Name Intercellular adhesion molecule 3 (ICAM3 Antibody Abstract)
Background

Target Description: This antibody recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM3 (Leucocyte Workshop VI). It is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This CD50 antibody is excellent for staining of formalin/paraffin tissues.

Gene Symbol: ICAM3

Gene ID 3385
UniProt P32942
Application Notes Functional Activity (Blocking): Blocks CD50-CD11a interaction
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS ( pH 7.4), BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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