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ICAM-3/CD50 antibody

ICAM3 Reactivity: Human FACS, IF, IHC, Func, BP Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6297704
  • Target See all ICAM-3/CD50 (ICAM3) Antibodies
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    Reactivity
    • 109
    • 3
    • 2
    • 2
    Human
    Host
    • 66
    • 42
    • 1
    Mouse
    Clonality
    • 69
    • 40
    Monoclonal
    Conjugate
    • 58
    • 10
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM-3/CD50 antibody is un-conjugated
    Application
    • 59
    • 49
    • 44
    • 34
    • 26
    • 23
    • 21
    • 13
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Functional Studies (Func), Blocking Peptide (BP)
    Purpose
    Mouse anti-Human CD50 Antibody [Sodium Azide Free]
    Specificity
    Cell surface
    Purification
    Stimulated human leukocytes were used as the immunogen for this CD50 antibody.
    Immunogen
    Stimulated human leukocytes were used as the immunogen for this CD50 antibody.
    Top Product
    Discover our top product ICAM3 Primary Antibody
  • Application Notes
    Functional Activity (Blocking): Blocks CD50-CD11a interaction
    FACS: 0.5-1 μg/million cells
    IF: 0.5-1 μg/mL
    IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    Restrictions
    For Research Use only
  • Buffer
    In 1X PBS ( pH 7.4), BSA free, sodium azide free
    Preservative
    Azide free
    Storage
    4 °C,-20 °C
    Storage Comment
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    Alternative Name
    Intercellular adhesion molecule 3 (ICAM3 Products)
    Synonyms
    CD50 antibody, CDW50 antibody, ICAM-R antibody, ICAM-3 antibody, ICAM3 antibody, intercellular adhesion molecule 3 antibody, ICAM3 antibody, Icam3 antibody
    Background

    Target Description: This antibody recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM3 (Leucocyte Workshop VI). It is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This CD50 antibody is excellent for staining of formalin/paraffin tissues.

    Gene Symbol: ICAM3

    Gene ID
    3385
    UniProt
    P32942
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