ICAM-3/CD50 antibody
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- Target See all ICAM-3/CD50 (ICAM3) Antibodies
- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ICAM-3/CD50 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Functional Studies (Func), Blocking Peptide (BP)
- Purpose
- Mouse anti-Human CD50 Antibody [Sodium Azide Free]
- Specificity
- Cell surface
- Purification
- Stimulated human leukocytes were used as the immunogen for this CD50 antibody.
- Immunogen
- Stimulated human leukocytes were used as the immunogen for this CD50 antibody.
- Top Product
- Discover our top product ICAM3 Primary Antibody
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- Application Notes
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Functional Activity (Blocking): Blocks CD50-CD11a interaction
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
- Preservative
- Azide free
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
- Alternative Name
- Intercellular adhesion molecule 3 (ICAM3 Products)
- Synonyms
- CD50 antibody, CDW50 antibody, ICAM-R antibody, ICAM-3 antibody, ICAM3 antibody, intercellular adhesion molecule 3 antibody, ICAM3 antibody, Icam3 antibody
- Background
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Target Description: This antibody recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM3 (Leucocyte Workshop VI). It is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This CD50 antibody is excellent for staining of formalin/paraffin tissues.
Gene Symbol: ICAM3
- Gene ID
- 3385
- UniProt
- P32942
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