CD6 antibody

Catalog No. ABIN6297741

The Mouse Monoclonal anti-CD6 antibody (ABIN6297741) specifically detects CD6 in IHC. The antibody is reactive with Human samples.

Quick Overview for CD6 antibody (ABIN6297741)

Target: CD6

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CD6 Antibody

Purpose: Mouse anti-Human CD6 Antibody [IHC only]

Specificity: Cell surface and cytoplasmic

Purification: The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody.

Immunogen: The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody.

Application Details

Application Notes: Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Handling

Buffer: Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD6

Target: CD6

Alternative Name: T-cell differentiation antigen CD6

Background:

Target Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular ""scavenger receptor cysteine-rich "" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. It shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. CD6 antibody can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Gene Symbol: CD6

Gene ID: 923

UniProt: P30203