Transferrin Receptor antibody

Catalog No. ABIN6297749

The Mouse Monoclonal anti-Transferrin Receptor antibody has been validated for FACS, WB and IF. It is suitable to detect Transferrin Receptor in samples from Human.

Quick Overview for Transferrin Receptor antibody (ABIN6297749)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Transferrin Receptor Antibody

Purpose: Mouse anti-Human Transferrin Receptor Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: The KG1 acute myeloid leukemia cell line was used as the immunogen for this Transferrin receptor antibody.

Immunogen: The KG1 acute myeloid leukemia cell line was used as the immunogen for this Transferrin receptor antibody.

Application Details

Application Notes: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 0.25-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: Transferrin receptor protein 1 ]

Background:

Target Description: This antibody recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa (Workshop IV). The antibody is highly specific to transferrin receptor and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Gene Symbol: TFRC

Gene ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis