NDE1 antibody

Catalog No. ABIN630785

Product Details anti-NDE1 Antibody

Target: NDE1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDE1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purified

Immunogen: NDE1 antibody was raised using a synthetic peptide corresponding to a region with amino acids AHRGPSSSLNTPGSFRRGLDDSTGGTPLTPAARISALNIVGDLLRKVGAL

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

NDE1 Blocking Peptide, catalog no. 33R-1254, is also available for use as a blocking control in assays to test for specificity of this NDE1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NDE1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for NDE1

Target: NDE1

Alternative Name: NDE1 (NDE1 Products)

Background: NDE1 is required for centrosome duplication and formation and function of the mitotic spindle. It is essential for the development of the cerebral cortex. NDE1 may regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron.

Molecular Weight: 38 kDa (MW of target protein)