HSD11B2 antibody

Catalog No. ABIN631485

The Rabbit Polyclonal anti-HSD11B2 antibody (ABIN631485) specifically detects HSD11B2 in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HSD11B2 antibody (ABIN631485)

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD11B2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSD11B2 Antibody

Purification: Affinity purified

Immunogen: HSD11 B2 antibody was raised using a synthetic peptide corresponding to a region with amino acids ERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRL

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HSD11B2 Blocking Peptide, (ABIN938104), is also available for use as a blocking control in assays to test for specificity of this HSD11B2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HSD10 2 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for HSD11B2

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Alternative Name: HSD11B2

Background: HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Molecular Weight: 45 kDa (MW of target protein)

Pathways: Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones