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Prohibitin antibody (C-Term)

PHB Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN634116
  • Target See all Prohibitin (PHB) Antibodies
    Prohibitin (PHB)
    Binding Specificity
    • 16
    • 13
    • 12
    • 12
    • 9
    • 9
    • 9
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 133
    • 62
    • 60
    • 11
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 112
    • 21
    Rabbit
    Clonality
    • 103
    • 30
    Polyclonal
    Conjugate
    • 66
    • 12
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Prohibitin antibody is un-conjugated
    Application
    • 101
    • 51
    • 46
    • 25
    • 20
    • 19
    • 14
    • 13
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    Prohibitin antibody was raised against the C terminal of PHB
    Purification
    Affinity purified
    Immunogen
    Prohibitin antibody was raised using the C terminal of PHB corresponding to a region with amino acids AEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLS
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    Discover our top product PHB Primary Antibody
  • Application Notes
    WB: 1-2 µg/mL, IHC: 4-8 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    Prohibitin Blocking Peptide, catalog no. 33R-1146, is also available for use as a blocking control in assays to test for specificity of this Prohibitin antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PHB antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    Prohibitin (PHB)
    Alternative Name
    Prohibitin (PHB Products)
    Synonyms
    phb1 antibody, MGC75944 antibody, PHB antibody, Phb antibody, ACYPI000080 antibody, phb antibody, PHB1 antibody, Bap32 antibody, sr:nyz128 antibody, wu:fa18f07 antibody, wu:fb09f05 antibody, prohibitin1 antibody, xphb1 antibody, prohibitin antibody, prohibitin-2 antibody, prohibitin L homeolog antibody, PHB antibody, phb antibody, LOC484431 antibody, LOC5576054 antibody, Phb antibody, phb.L antibody
    Background
    Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
    Molecular Weight
    30 kDa (MW of target protein)
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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