NKIRAS1 antibody (AA 50-130)

Catalog No. ABIN7229232

The Rabbit Polyclonal anti-NKIRAS1 antibody (ABIN7229232) specifically detects NKIRAS1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for NKIRAS1 antibody (AA 50-130) (ABIN7229232)

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKIRAS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NKIRAS1 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-KBRS1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of KBRS1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human KBRS1 protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NKIRAS1

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Alternative Name: KBRS1

Background: NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1, KappaB-Ras1NKIRAS1 (NFKB Inhibitor Interacting Ras Like 1) is a Protein Coding gene. Among its related pathways are NF-KappaB Family Pathway. Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Molecular Weight: 21kD

Gene ID: 28512

UniProt: Q9NYS0