ALG11 antibody
Quick Overview for ALG11 antibody (ABIN634995)
Target
See all ALG11 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- ALG11 antibody was yeast alpha-12-mannosyltransferase
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Purification
- Affinity purified
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Immunogen
- ALG11 antibody was raised using a synthetic peptide corresponding to a region with amino acids LSEDLGVQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMA
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Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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ALG11 Blocking Peptide, (ABIN5612018), is also available for use as a blocking control in assays to test for specificity of this ALG11 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ALG11 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- ALG11 (Asparagine-Linked Glycosylation 11, alpha-1,2-Mannosyltransferase Homolog (Yeast) (ALG11))
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Alternative Name
- ALG11
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Background
- ALG11 is a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP).
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Molecular Weight
- 56 kDa (MW of target protein)
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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