DIABLO
Reactivity: Human
IHC, ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:500-1:1,000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Concentration
Lot specific
Buffer
Affinity purified IgG supplied in PBS with 0.02 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
DIABLO
(Second Mitochondria-Derived Activator of Caspase (DIABLO))
Alternative Name
DIABLO
Background
DIABLO (direct IAP binding protein with low pI) is a novel protein that can bind mammalian IAP homolog A (MIHA, also known as XIAP), and can also interact with MIHB and MIHC and the baculoviral IAP, OpIAP. DIABLO may promote apoptosis by binding to IAPs and preventing them from inhibiting caspases.