NDUFA13 antibody (AA 159-172)

Catalog No. ABIN636278

Product Details anti-NDUFA13 Antibody

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Binding Specificity: AA 159-172

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA13 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): This antibodys immunogens shares 85 % sequence identity with its Mouse and rat homologs.

Purification: Affinity chromatography purified

Immunogen: GRIM19 antibody was raised in rabbit using AA 159-172 QAETDRRTLQMLRE of the human GRIM-19 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Alternative Name: GRIM19 (NDUFA13 Products)

Synonyms: GRIM-19 antibody, Ndufa13 antibody, B16.6 antibody, CDA016 antibody, GRIM19 antibody, 2700054G14Rik antibody, AU022060 antibody, CGI-39 antibody, Grim19 antibody, RGD1565358 antibody, YJEFN3 antibody, NADH:ubiquinone oxidoreductase subunit A13 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 antibody, cell death-regulatory protein GRIM19 antibody, GRIM-19 protein antibody, NADH:ubiquinone oxidoreductase subunit A13 L homeolog antibody, ndufa13 antibody, LOC655421 antibody, Ndufa13 antibody, CpipJ_CPIJ000908 antibody, Bm1_18845 antibody, ndufa13.L antibody, NDUFA13 antibody

Background: Antisense expression of Genes associated with Retinoid-IFN-induced Mortality (GRIM), GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination.

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling