NDUFA13 antibody (AA 159-172)

Catalog No. ABIN636278

The Rabbit Polyclonal anti-NDUFA13 antibody is suitable to detect NDUFA13 in samples from Human. It has been validated for WB.

Quick Overview for NDUFA13 antibody (AA 159-172) (ABIN636278)

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDUFA13 Antibody

Binding Specificity: AA 159-172

Cross-Reactivity (Details): This antibodys immunogens shares 85 % sequence identity with its Mouse and rat homologs.

Purification: Affinity chromatography purified

Immunogen: GRIM19 antibody was raised in rabbit using AA 159-172 QAETDRRTLQMLRE of the human GRIM-19 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for NDUFA13

Target: NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))

Alternative Name: GRIM19

Background: Antisense expression of Genes associated with Retinoid-IFN-induced Mortality (GRIM), GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination.

Pathways: Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling