Dopamine Receptor d1 antibody

Catalog No. ABIN636878

The Rabbit Polyclonal anti-Dopamine Receptor d1 antibody is suitable to detect Dopamine Receptor d1 in samples from Human. It has been validated for ELISA and IHC (p).

Quick Overview for Dopamine Receptor d1 antibody (ABIN636878)

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dopamine Receptor d1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Dopamine Receptor d1 Antibody

Purification: Affinity chromatography purified

Immunogen: DRD1 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Application Details

Application Notes: IHC-P: 1-5 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Target Details for Dopamine Receptor d1

Target: Dopamine Receptor d1 (DRD1) (Dopamine Receptor D1 (DRD1))

Alternative Name: DRD1

Background: Dopamine receptors are a class of metabotropic G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Activation of D1-like family receptors is coupled to the G protein G alphas, which subsequently activates adenylyl cyclase, increasing the intracellular concentration of the second messenger cyclic adenosine monophosphate (cAMP).

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Protein targeting to Nucleus, Feeding Behaviour, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity