IDO1 antibody

Catalog No. ABIN6390524

The Rabbit Polyclonal anti-IDO1 antibody (ABIN6390524) specifically detects IDO1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IDO1 antibody (ABIN6390524)

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IDO1 Antibody

Purpose: Unconjugated Rabbit polyclonal to I23O1

Specificity: I23O1 Polyclonal Antibody detects endogenous levels of protein.

Purification: I23O1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Comment:

Expressed in mature dendritic cells located in lymphoid organs (including lymph nodes, spleen, tonsils, Peyers's patches, the gut lamina propria, and the thymic medulla), in some epithelial cells of the female genital tract, as well as in endothelial cells of term placenta and in lung parenchyma . Weakly or not expressed in most normal tissues, but mostly inducible in most tissues . Expressed in more than 50% of tumors, either by tumoral, stromal, or endothelial cells (expression in tumor is associated with a worse clinical outcome) . Not overexpressed in tumor-draining lymph nodes .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for IDO1

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Alternative Name: I23O1

Molecular Weight: 44 kDa

Gene ID: 3620

UniProt: P14902

Pathways: Activated T Cell Proliferation