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LAG3 antibody (Internal Region)

Verified LAG3 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN6391370
  • Target See all LAG3 Antibodies
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Binding Specificity
    • 15
    • 14
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 87
    • 34
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 52
    • 35
    • 7
    • 3
    Goat
    Clonality
    • 52
    • 42
    • 1
    Polyclonal
    Conjugate
    • 51
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAG3 antibody is un-conjugated
    Application
    • 68
    • 35
    • 30
    • 29
    • 25
    • 22
    • 15
    • 13
    • 13
    • 10
    • 10
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    LAG3 / CD223
    Sequence
    EDVSQAQAGT YTCH
    Specificity
    This antibody is expected to recognize the extra-cellular domain.
    Cross-Reactivity
    Human
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Isotype
    IgG
    Top Product
    Discover our top product LAG3 Primary Antibody
  • Application Notes

    Western Blot: Approx 55 kDa band observed in Human Lymph Node and Tonsil lysates (calculated MW of 57.4 kDa according to NP_002277.4). Recommended concentration: 0.3-1 μg/mL.

    Peptide ELISA: antibody detection limit dilution 1:2000.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Target
    LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
    Alternative Name
    LAG3 (LAG3 Products)
    Synonyms
    CD223 antibody, LAG-3 antibody, Ly66 antibody, lymphocyte activating 3 antibody, lymphocyte-activation gene 3 antibody, LAG3 antibody, Lag3 antibody
    Background
    LAG3, lymphocyte activating 3, CD223, lymphocyte-activation gene 3
    Gene ID
    3902
    NCBI Accession
    NP_002277
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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