NPPB antibody
Quick Overview for NPPB antibody (ABIN639815)
Target
See all NPPB AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Mouse Anti-Human BNP / NPPB
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Specificity
- This product detects human brain natriuretic peptide (BNP), a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesised as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure. This product also detects proBNP.
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Characteristics
- Cardiac Markers
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Purification
- Purified
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Immunogen
- Human synthetic BNP.
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Isotype
- IgG1
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Application Notes
- ELISA, Immunoassay, Western Blotting
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Restrictions
- For Research Use only
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Concentration
- IgG concentration 1.0 mg/ml
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Buffer
- Phosphate buffered saline pH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- -20°C
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- NPPB (Natriuretic Peptide Precursor B (NPPB))
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Alternative Name
- BNP / NPPB
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Pathways
- Hormone Activity
Target
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