CD11b antibody

Catalog No. ABIN643792

Product Details anti-CD11b Antibody

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Mouse

Host: Rat

Conjugate: This CD11b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: DS-MB-03721 recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. DS-MB-03721 has been reported to block iC3b binding to its receptor (3). This product is routinely tested in flow cytometry on mouse peritoneal macrophages. Also reacts with human and rabbit CD11b.

Characteristics: Rat Anti-Mouse CD11b, low endotoxin

Endotoxin Level: <0.01EU/ug

Immunogen: T cell enriched splenocytes from B10 mice

Isotype: IgG2b

Application Details

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Storage: -20 °C

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: CD11b (ITGAM Products)

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation