IRAK4 antibody (N-Term)
Quick Overview for IRAK4 antibody (N-Term) (ABIN645843)
Target
See all IRAK4 AntibodiesReactivity
Host
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- The Goat Anti-IRAK4 (N Terminus) antibody detects protein derived from human recombinant protein and HELA lysate at various concentrations.
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Cross-Reactivity
- Human, Mouse (Murine), Monkey
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Characteristics
- Goat Anti-IRAK4 (N Terminus)
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Immunogen
- Peptide with sequence NKPITPSTYVRC, from the N Terminus of the protein sequence according to NP_057207.1.
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Isotype
- IgG
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Restrictions
- For Research Use only
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Reconstitution
- Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Minimize freezing and thawing cycles.
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Storage
- -20 °C
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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Alternative Name
- IRAK4
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Background
- Interleukin-1 receptor (see IL1R, MIM 147810)-associated kinases (e.g., IRAK1, MIM 300283) are important mediators in the signal transduction of Toll-like receptor (TLR, e.g., TLR4, MIM 603030) and IL1R family members, collectively referred to as TIRs. IRAK4 functions in this signal transduction pathway.
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NCBI Accession
- NP_057207
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Pathways
- NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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