SPRN antibody (C-Term)

Catalog No. ABIN2840007

This Rabbit Polyclonal antibody specifically detects SPRN in WB and IHC (p). It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for SPRN antibody (C-Term) (ABIN2840007)

Target: SPRN (Shadow of Prion Protein (SPRN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB25483

Product Details anti-SPRN Antibody

Binding Specificity: AA 76-105, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the C-terminal region of human SPRN.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-SPRN antibody (ABIN2840007)

Nyeste, Stincardini, Bencsura, Cerovic, Biasini, Welker: "The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells." in: Scientific reports, Vol. 6, pp. 36441, (2018) (PubMed).

Nyeste, Bencsura, Vida, Hegyi, Homolya, Fodor, Welker: "Expression of the Prion Protein Family Member Shadoo Causes Drug Hypersensitivity That Is Diminished by the Coexpression of the Wild Type Prion Protein." in: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4473-86, (2016) (PubMed).

Target Details for SPRN

Target: SPRN (Shadow of Prion Protein (SPRN))

Alternative Name: SPRN

Background: SPRN has PrP(C)-like neuroprotective activity. SPRN may act as a modulator for the biological actions of normal and abnormal PrP.

Molecular Weight: 14522

Gene ID: 503542

NCBI Accession: NP_001012526

UniProt: Q5BIV9