SMAD6 antibody (AA 358-386)
Quick Overview for SMAD6 antibody (AA 358-386) (ABIN651537)
Target
See all SMAD6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 358-386
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Predicted Reactivity
- M
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This SMAD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-386 amino acids from the Central region of human SMAD6.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Expiry Date
- 6 months
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- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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Alternative Name
- SMAD6
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Background
- SMAD6 belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling.
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Molecular Weight
- 53497
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Gene ID
- 4091
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NCBI Accession
- NP_001136333, NP_005576
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UniProt
- O43541
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Pathways
- Chromatin Binding
Target
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