STEAP2 antibody (AA 229-258)

Catalog No. ABIN651772

Product Details anti-STEAP2 Antibody

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Binding Specificity: AA 229-258

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STEAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-258 amino acids of human STEAP2.

Clone: RB26961

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000. WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for STEAP2

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Alternative Name: STEA2 (STEAP2 Products)

Synonyms: 4921538B17Rik antibody, AI930049 antibody, AW045895 antibody, IPCA-1 antibody, IPCA1 antibody, PCANAP1 antibody, STAMP1 antibody, STMP antibody, PUMPCn antibody, six transmembrane epithelial antigen of prostate 2 antibody, STEAP2 metalloreductase antibody, Steap2 antibody, STEAP2 antibody

Background: This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 56056

Gene ID: 261729

NCBI Accession: NP_001035755, NP_001035756, NP_001231873, NP_001231875, NP_694544

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis