CRB2 antibody (AA 1258-1285)

Catalog No. ABIN651911

Product Details anti-CRB2 Antibody

Target: CRB2 (Crumbs Homolog 2 (CRB2))

Binding Specificity: AA 1258-1285

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CRUM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1258-1285 amino acids of human CRUM2.

Clone: RB27068

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CRB2 antibody (ABIN651911)

Ebarasi, Ashraf, Bierzynska, Gee, McCarthy, Lovric, Sadowski, Pabst, Vega-Warner, Fang, Koziell, Simpson, Dursun, Serdaroglu, Levy, Saleem, Hildebrandt, Majumdar: "Defects of CRB2 cause steroid-resistant nephrotic syndrome." in: American journal of human genetics, Vol. 96, Issue 1, pp. 153-61, (2015) (PubMed).

Target Details for CRB2

Target: CRB2 (Crumbs Homolog 2 (CRB2))

Alternative Name: CRUM2 (CRB2 Products)

Background: May play a role in polarized cells morphogenesis.

Molecular Weight: 134265

Gene ID: 286204

NCBI Accession: NP_775960

UniProt: Q5IJ48

Pathways: Notch Signaling