WNT4 antibody (AA 211-239)

Catalog No. ABIN652224

Cited in 1 publication. The Rabbit Polyclonal anti-WNT4 antibody (Clone RB19965) (ABIN652224) specifically detects WNT4 in WB, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for WNT4 antibody (AA 211-239) (ABIN652224)

Target: WNT4 (Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: RB19965

Product Details anti-WNT4 Antibody

Binding Specificity: AA 211-239

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This WNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the Central region of human WNT4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Expiry Date: 6 months

References for anti-WNT4 antibody (ABIN652224)

Fang, Zeng, Wang, Liu, Xu, Dai, Zhao, Zhang, Liang, Chen, Shi, Zhang, Wang, Qiao, Shi: "Estimated diversity of messenger RNAs in each murine spermatozoa and their potential function during early zygotic development." in: Biology of reproduction, Vol. 90, Issue 5, pp. 94, (2014) (PubMed).

Target Details for WNT4

Target: WNT4 (Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))

Alternative Name: WNT4

Background: The WNT family consists of secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT4 is a protein which shows 98 % amino acid identity to the Wnt4 protein of mouse and rat. It play a concerted role in both the control of female development and the prevention of testes formation.

Molecular Weight: 39052

Gene ID: 54361

NCBI Accession: NP_110388

UniProt: P56705

Pathways: WNT Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cell-Cell Junction Organization, Tube Formation