Hexosaminidase A antibody (AA 315-343)

Catalog No. ABIN652263

The Rabbit Polyclonal anti-Hexosaminidase A antibody (Clone RB20993) (ABIN652263) specifically detects Hexosaminidase A in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Hexosaminidase A antibody (AA 315-343) (ABIN652263)

Target: Hexosaminidase A (HEXA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hexosaminidase A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB20993

Product Details anti-Hexosaminidase A Antibody

Binding Specificity: AA 315-343

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HEXA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-343 amino acids from the Central region of human HEXA.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Hexosaminidase A

Target: Hexosaminidase A (HEXA)

Alternative Name: HEXA

Background: HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases.

Molecular Weight: 60703

Gene ID: 3073

NCBI Accession: NP_000511

UniProt: P06865

Pathways: Sensory Perception of Sound, Glycosaminoglycan Metabolic Process